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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43d3002da5d41931e4f15c7ba6631a32483f0eb53565550ffdaaf3a524eafe5' 
  AND token = 'zgVPZHX+YbEatrc3/C2MZsj7fdBo9/1RAiY4nmcDFzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}