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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295424a4a1386078b25369f6265e1f12672dd0631ac55d7e8150d280f4fe887f' 
  AND token = 'Ovl5qDhMr4qRBynOJvcMLaKlqslTenVPpr1D0Gjlrdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}