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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d52240bea93bb275e1482f7e9e0de8bd6a272edc7ca464562b144e00deb48b4' 
  AND token = 'TC3HFeRuh3c3tjIrV3szggtpx0zTo42ipsrVeMh5Zd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}