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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14b55d2333068a51c2b25cb5a03afe5a79cf33feef4c20a2b01511da2a8d8577' 
  AND token = 'vr6dYGOCcKlZ8OQGGv7b9ir/WUDucEKt8p0UbGHdv4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}