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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88ead75adae549ebd1834f4de9e1c6c5c7fef8191f43be331ed133d9527fc58a' 
  AND token = '2OKHC9vUGi2pzySdo6K2HHp9coHicFgkxJEUg3VD2Tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}