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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad5ed3e83834addec78ec1702c5a7a8468c459ed06e0c8f07414e1524415696' 
  AND token = 'hyuQH49BNN+64RNR4Y1+tEJNRLbPpkvqyV99ivVC80Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}