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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '625d84066c6dca38a89f3c1a02360ba3d99be709361076c8a02775e39764c294' 
  AND token = '78elyiiN8ywADsOCfH+BACIr9jTqrf4AVlJswPUBDrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}