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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c782e260c376658add360c3727c55b02b695bae4415ae62b0f9656e8778ef3df' 
  AND token = '/GJcl5FXW25omzWS6txLVeCUEnReIZSjxresPhs+74Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}