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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13a2741f2c77dbe5c132c5406fb5e6e0a1bc38e0a24d7af978d72ad678735279' 
  AND token = 'USHotF05dfq0Q6EydDBkBygPuISsG8v471pANbpKHDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}