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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88df861d5262520abe0dbac28ccb7fde1f1cc953fb9c3f4420f343e51d64363f' 
  AND token = 'AWqmFOM3UyW5fkwE0F9RAVShrkg7fwkUcgwFmFKg1+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}