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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d766d511657a278b556bd492de0d1b4aa91aaa1eac6c72c29a05b177033d294' 
  AND token = 'kEdQBWY/g9gpiN3W01dRvKDdJ/vKgQhqz6HudZzAAvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}