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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69322d4340ec3f89cf47e1c322c98e4280fa914f9c474d71a6916fc1491f41bb' 
  AND token = 'PY28BOFp2ZrY/m+cg1DxNvrY3AMx0j/ZbWYhOtgNq7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}