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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f06612e57b566452c60c9504bd2a9ba3b34a81316864c5919386e6870051a6ec' 
  AND token = 'hDKxfw72eTiRkT03bZ7hrB10rQsuS/uioQFE/RN6Ad4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}