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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ff48e7652cc0979685111ab586f83fed8bf4e4e87cc2fa38673c444a667acae' 
  AND token = 'INpwH2etvfRxxF3ekKdx7N4CeWguM2suykRbWUMlSNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}