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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ee276fdc107bc35e9bcaf4ad640f34de46702f2062911c35bcd83fc28f3b116' 
  AND token = 'betv1/LE/CYQ82G1fK/IxsLnrA9aOoJtt5dwZHy6jxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}