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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fbc09f260feab8d98fe9f73e1ba35c687e1d3685ea324e68572bcd64a11b390' 
  AND token = '+DTGKmen5xS+n+lwws5GB0qSIo9TK56w3sw88U016EQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}