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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86c89b1f2fb29aa63b5ecd9cb424cf0483a86c095c3985a9a46ce97634eb2c82' 
  AND token = 'slBHmTtIDQn0fg/vbaUBWUZlQVOETcxIpzbN5OS3ZlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}