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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da9a3d07968ad27817adb3c0f787614c71410ec527670b648f7b46eca1368767' 
  AND token = 'LBaDPy2KPAdFhpSQ0Key/tv5QlE84bQnY8QglpHhUzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}