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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c63f6839893c12c7e72be86ced1a2399855b508c8621c28624dc2b187a209e' 
  AND token = 'yVJhiPea2kGY5E22/8REUnvNc84ffV6ntxuLPcX603k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}