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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd22070ddedf36059b0a29615752797622edddc05b22daaaa15a5e785dde7ef3' 
  AND token = 'F29L8tI6FTXTi2owP/6B99xc2TYTOxCCeVnVBRP3eAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}