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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a1af5d68a4d04a98be96047328afee517a7b5497fd27e75e2e9df826f70c28c' 
  AND token = 'Qw0XgTDZgIWIMD1Ar+VjpugmmfIlrQl7lEYirbmax1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}