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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '244b4425e8f0fb7adb8ca18669f7f4a7d2bae51b3a9f54a17d47c4bdd2da7384' 
  AND token = 'SO0UdCp6FUe0KN1eMLKpxk5GjU8SU9pxd2JOHgDxLo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}