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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '869fd4004ec17af603f01873c5a3924abd1f8992fcdedb011c7a6e0ecec19ab2' 
  AND token = '5iimCu1Gl+mud0AycJ4w94kaKQIvMMOmD0rvDfCxQAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}