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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ede5f20ff81e244cd6e53a51d6937734be7ad1769e315a866a8ddc5cc6b5238' 
  AND token = 'h8pUJQi2mt++/DhteRO2RCHZ9C7/dx2MgsrKMvy/lhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}