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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '636b5be20e66ef5348f72f29ab8e7195cc133fe8632e71ae726adb79b9e03dd2' 
  AND token = 'QQw2lfkoQaeGym9Bt+HdYFwFreGGY3H4bwMrYsRigks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}