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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d4717e9e1a4271638d571bba1fa0d2beaa0b4a01564c747002db33c963764c' 
  AND token = 'O74XDVWbXkPStgbGkewSzY04fLEfyH3AgrZsu3gGVuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}