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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c0d92758285e873e2eab48d4ec8b3b57ae538f39be78fbe811849fc641e2fe2' 
  AND token = 'c3s+SPH4eKwdGpCAAlIli/tTwngeSDXQbMD84aZ/7XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}