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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3871d2e2780062a3c0d3d13faf3eeb68f8135156e5f86e287affc15211f50fae' 
  AND token = '6/oDTJLRT0gfLsbizC+ibiBv5rPHlb1fQdHUldcToqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}