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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f916b09aa0ee59bded12f97256e99e3aef78d37316402bfab54f503ac7e8f09' 
  AND token = 'RL9E0QExUCqHanjVQqpG7MnbZB+JpjP5r6XRGGrclvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}