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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5905bf408788ce6704b526ec40205d4b289a67ebe64ccc46fd8f08d35bf4ed87' 
  AND token = 'EKx3NX5tCqehVyJwQSSoNLMo3j9QovaCQVoO3/jVXE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}