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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd47a9cbb90a134dee48e5897e12dc4426d0d7d71b160c0e6c450074588707bdd' 
  AND token = 'X04Kz4E3b513LI/6UY0i4DGuOS8MHM16aRUEbn6xJSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}