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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aa19c64843f505d1a85903d50c7cb3723fbf39d3de1646d954e7e5083fdc553' 
  AND token = 'dLMY227h04WPf9aJSr6hPoJbOElJddXO6fqJeAFrKxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}