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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '874035fd1c31bd97f9175aeb17f34b72214e57828437e74b84e170cf22c55aed' 
  AND token = 'rDt3qzCR4+SU7Sth64MnL1TYHMyNPjSuo2XGh+zDiWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}