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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e85b2d5058ca10125326278dbd7e2e88e455b5b708bce34aee676f48b72303ee' 
  AND token = 'TPZxGVbmB+5F5RWJ6vsayRA7Fk2wTB3GpxXbt2SCb2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}