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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9de2263e62703c8d88422a13c924c7fd10b1628be0081b80772f3769fef54261' 
  AND token = 'zKtTOap667npt/ycfQf5GUbGyERWuMBEQqajg6pmHWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}