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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740b711a566f2b1cdda46dceac77fe78d32112fc8621b172951e43ea2e8ea762' 
  AND token = 'VqwaT7OO6OBHL2gyKhbV4S+OQ3liue/0/7D6BAW21Rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}