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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e112c48d701718b90a2b31285c9446b2caf7434f7e23f2fa4d896ea80270cec8' 
  AND token = '1vy5UQK/s4PS79Ak8mYG7z0zb3V/vrsqKiOtItY6+4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}