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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '004a7f06dabc152c7cd68700e439bd12a29f626fd4bcf8cbbe33a5f8d5602555' 
  AND token = 'zRVwIio3mKze2tQPyechqUFy+EzKhZF1EbBw6Ak1BWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}