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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '182f86d128ab9e4b0c9fa8b59b1b8d5bd3e2879bf1c74f426d629bcdaee26141' 
  AND token = 'ZATFeITyPgi7sjMQh83Uw+U/4TfxmkIZqKbM5SA9KvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}