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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601434e752ac2389549c58e66ab7434bd2992b5a25ee65469695db8ed0bcb717' 
  AND token = 'NMGAgnOEB4UxNKGq6bw7U10Yj8WGWzfndaXselM0iik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}