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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed8d0f83cff57161b9429b056e30c98ba1a25bfd9e18a7c9bde1ab8ce6163ad' 
  AND token = 'y06w2oniwCICXaKYYqYy3fYKEZ35wPS6TjQRy+jzLcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}