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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '201859d0a51eb3c60c456d1963b0145d90c5ae2c88e9f2d05c92451102dd3979' 
  AND token = 'Bgy7W6sbTJ2esrQUi8tGLvWcN0UrpIsPrZsUGj6BzZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}