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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c506efd60afe9d29cb0bc03e68c01748775a1615e1b583d48ef17ec3469a8f4' 
  AND token = 'HGoLS3dh/Lf/svzPM74INaDad0v8dMTIbOHFVWv73VQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}