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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '498b107616825bf0975f50920f51f00ecba46851f790943b8e2a9f3a5e444f19' 
  AND token = 'OB+O/b4k3NWxCoeydBX+CL5CAwBtCKdaLzZxLM28bjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}