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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c1ddc3d3d942f4de4fd99606d7677fdfdd894d5407fc8b2f0d85aa4a9b3394e' 
  AND token = 'NQRrznDZQ6gpNu6dwqp+Yr6HqNjJTszkMFNpKup8rJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}