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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b18718b9e5f7563ff102e165b38af4f06c327a47819c9ed10868fc03239c8686' 
  AND token = 'qig1a7rwqo1lpA7z3rGyTB0KJYiWAODGeOP00mEC9Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}