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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8755d86ee0c13c7d55243901604559193829c40bff4dced8c1fad82ab5afc1b' 
  AND token = 'gQJm6JdfTa2rlA1g+UbRK2D59gG4tLCPpzKj+sl+kwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}