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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e606e2ec9757bf883b4f1ceb78b90cbaa36340f21e91f9373e037215b5204b' 
  AND token = '9Q8d+BsznnEvCbeVtruBeYrSQVB4fScXvVxXhXM7xfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}