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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01ebe1880de666246a5429b3abfcbba065528c262d0d21988e2b0572911a0b6b' 
  AND token = 'tuZfijusY+yfmonCJAc1aOPPcEq4O9P8c2nfZ4VCLtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}