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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f45dbec4686035699cfa215bbe42a665e593539741b39a4f847fd85667d9767' 
  AND token = 'JnOidvf39kHBOB5/UMqvTCl4co24KErjTo1omNAicDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}